Synthesis and structure–activity relationships of novel IKK-β inhibitors. Part 2: improvement of in vitro activity

T Murata, M Shimada, H Kadono, S Sakakibara…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 15 p. 4013 - 4017

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Citation Number: 57

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... were exemplified as the starting aldehyde in the reported procedure, 3 we found that various aliphatic aldehydes could also be used in the pyridine construction reaction using traditional and combinatorial chemistry approaches, 4 as ...