Syntheses of two potential food mutagens

…, WW Bradford, JE Bupp, JA Kozocas

Index: Tanga; Bradford; Bupp; Kozocas Journal of Heterocyclic Chemistry, 2003 , vol. 40, # 4 p. 569 - 573

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Citation Number: 7

Abstract

Our diet is a complex mixture that provides nutritional sustenance but may also be important in the causation, modulation, and prevention of human disease. Cooking, heat processing, and pyrolysis of protein-rich foods induce formation of mutagenic and carcinogenic hetero- cyclic amines through chemical reactions involving amino acids, creatine, and proteins [1,2]. The formation of these compounds requires high temperatures, such as are found in radiative or ...