Amino Analogs of Firefly Luciferin and Biological Activity Thereof1

EH White, H Wörther, HH Seliger…

Index: White,E.H. et al. Journal of the American Chemical Society, 1966 , vol. 88, p. 2015 - 2019

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Citation Number: 102

Abstract

Abstract: For our study of the mechanism of firefly bioluminescence, the compounds 2-(6'- amino-2 '-benzothia-zoly1)-A2-thiazoline-4-carboxylic acid (IVa,“aminoluciferin”), 2-(6'- acetylamin~-2'-benzothiazolyl)-Az-thiaz~ line-4-carboxylic acid (IVb), and 2-(6'- trifluoroacetylamino-2'-benzoth~ azolyl)-A2-thiazoline-4-carboxylic acid (IVc) have been synthesized and characterized. Of these compounds, only aminoluciferin reacts with firefly ...