Lithium triflate (LiOTf): a highly efficient and reusable catalytic system for the synthesis of diversified quinolines under neat conditions

AB Atar, SD Dindulkar, YT Jeong

Index: Atar, Amol B.; Dindulkar, Someshwer D.; Jeong, Yeon Tae Monatshefte fur Chemie, 2013 , vol. 144, # 5 p. 695 - 701

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Citation Number: 12

Abstract

Abstract A series of diverse polyfunctionalized quinolines were easily prepared in excellent yields via a Friedlander reaction of o-aminoaryl ketone or o-aminoaryl aldehyde with α- methylene ketones using lithium triflate as an expeditious catalyst under solvent free conditions. The protocol provides a practical and straightforward approach toward highly functionalized quinoline derivatives in excellent yields. The catalyst is easily recoverable ...