Facile and scalable preparation of 2-imidazolylpyridines

…, MR Anneser, D Jantke, M Cokoja, WA Herrmann…

Index: Raba, Andreas; Anneser, Markus R.; Jantke, Dominik; Cokoja, Mirza; Herrmann, Wolfgang A.; Kuehn, Fritz E. Tetrahedron Letters, 2013 , vol. 54, # 26 p. 3384 - 3387

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Citation Number: 14

Abstract

A novel method for the synthesis of 2-imidazolylpyridines is presented. The reaction of 2- halopyridines, potassium carbonate, and imidazole at high temperatures under inert gas atmosphere leads exclusively to the formation of 2-imidazolylpyridines in high yields. The synthesis is scalable, comparatively inexpensive, and the products are easily isolable.

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