Tetrahedron

Electrochemical cross-coupling between 2-halopyridines and aryl or heteroaryl halides catalysed by nickel-2, 2′-bipyridine complexes

C Gosmini, S Lasry, JY Nedelec, J Perichon

Index: Gosmini, Corinne; Lasry, Sarah; Nedelec, Jean-Yves; Perichon, Jacques Tetrahedron, 1998 , vol. 54, # 7 p. 1289 - 1298

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Citation Number: 58

Abstract

2-Arylpyridines can be obtained in good to high yields by electrochemical reduction using the sacrificial anode process and catalysis by nickel-2, 2′-bipyridine (bpy) complexes. In a first approach functionalized arylzinc species are prepared in DMF as solvent by electrolytic reduction of the corresponding aryl-bromides or-chlorides in the presence of ZnBr2 and Ni (II)-bpy complexes and then coupled with 2-chloropyridine. In a second approach the ...