Concise synthesis of dihydrochalcones via palladium-catalyzed coupling of aryl halides and 1-aryl-2-propen-1-ols
…, R Brouillard, A Wagner, C Mioskowski
Index: Briot, Anne; Baehr, Corinne; Brouillard, Raymond; Wagner, Alain; Mioskowski, Charles Journal of Organic Chemistry, 2004 , vol. 69, # 4 p. 1374 - 1377
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Citation Number: 45
Abstract
An expedient route to substituted dihydrochalcones is reported. The key step is a palladium- assisted arylation of 1-aryl-2-propen-1-ols. This two-step/one-purification process allows the synthesis of a wide range of compounds with original substitution patterns, including polyphenolic derivatives.
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