Tetrahedron

Aromatic nucleophilic substitution reactions of 1-dialkylamino-substituted activated benzenes with various amines in dimethyl sulfoxide

S Sekiguchi, H Ishikura, Y Hirosawa, N Ono

Index: Sekiguchi, Shizen; Ishikura, Hiromi; Hirosawa, Yukitoshi; Ono, Nobuyuki Tetrahedron, 1990 , vol. 46, # 16 p. 5567 - 5578

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Citation Number: 19

Abstract

In the reactions of 1-d1a1kylamino-2, 4, 6-trinitro-and 1-dialkylam1no-2, 4-dinitrobenzenes with various amines in dimethyl sulfoxide, 1-dialkylamino group is easily replaced with primary n-alkylamines at room temperature, and in a low yield with pyrrolidine only among secondary amines.

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