Total syntheses of epothilones B and d

JC Jung, R Kache, KK Vines, YS Zheng…

Index: Journal of Organic Chemistry, , vol. 69, # 26 p. 9269 - 9284

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Citation Number: 47

Abstract

... The Journal of Organic Chemistry. ... epothilone B (2). 3a Another strategy employed an aldol reaction between aldehyde E and keto acid F to provide the C6−C7 bond of acid D, which could then undergo ring closure via macrolactonization to give epothilone B (2). 3b , c,e,j,n In ...