A Facile Workup-Free Catalytic Rearrangement of Epoxides on Immobilized Organoaluminum Columns.

S Nagahara, K Maruoka, H Yamamoto

Index: Nagahara, Shigeru; Maruoka, Keiji; Yamamoto, Hisashi Chemistry Letters, 1992 , # 7 p. 1193 - 1196

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Citation Number: 8

Abstract

Chemistry Letters, 1 9 9 2 1195 First, we studied the epoxide rearrangement with the polymeric aluminum reagent 2 (20 mol%) in a conventional batch method as a test of its applicability to the flow method on a column. Treatment of sterically hindered triphenol 13) (0.13 mmol) in degassed CH2C12 (10 mL) with Me3Al (0.2 mmol) at room temperature for 1 h gave rise to the polymeric aluminum reagent 2. For example, rearrangement of the tert- butyldimethylsilyl ether of ...