Tetrahedron

Highly diastereoselective synthesis of spiro [cyclopropane-1, 3′-indolin]-2′-ones via catalyst-free cyclopropanation using ethyl diazoacetate

RA Maurya, CN Reddy, GS Mani, JS Kapure…

Index: BOEHRINGER INGELHEIM INTERNATIONAL GMBH Patent: US2011/195954 A1, 2011 ;

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Citation Number: 7

Abstract

Substituted 3-methyleneindolin-2-ones were efficiently cyclopropanated with ethyl diazoacetate to yield spiro[cyclopropane-1,3′-indolin]-2′-ones in a cataly.