Organic letters

Efficient 2-aryl benzothiazole formation from aryl ketones and 2-aminobenzenethiols under metal-free conditions

Y Liao, H Qi, S Chen, P Jiang, W Zhou, GJ Deng

Index: Liao, Yunfeng; Qi, Hongrui; Chen, Shanping; Jiang, Pengcheng; Zhou, Wang; Deng, Guo-Jun Organic Letters, 2012 , vol. 14, # 23 p. 6004 - 6007

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Citation Number: 40

Abstract

2-Aryl benzothiazole formation from aryl ketones and 2-aminobenzenethiols under metal- and I2-free conditions was described. Various 2-aryl benzothiazoles were selectively obtained in good yields using molecular oxygen as oxidant. DMSO played an important role in this transformation. Functional groups such as methyl, methoxy, fluoro, chloro, bromo and nitro groups were tolerated under the optimized reaction conditions.

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