Synthesis

Synthesis of Chiral n, n+ 1-Diamino Acids and their Application to the Construction of Dendrimers

E Bellis, T Markidis, G Kokotos

Index: Bellis, Evagelos; Markidis, Theodoros; Kokotos, George Synthesis, 2002 , # 10 p. 1359 - 1364

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Citation Number: 7

Abstract

Abstract Efficient methods for the synthesis of chiral n, n+ 1-diamino acids starting from l- glutamic acid were developed. A second generation prototype amino acid based dendrimer, containing 1, 3-propanediamine as the core and 4, 5-diaminopentanoic acid as the branching unit, was synthesised following the divergent approach. Diaminobutane poly (propyleneimine) dendrimers modified at the periphery with n, n+ 1-diamino acids were ...