Unexpected enhancement of thrombin inhibitor potency with o-aminoalkylbenzylamides in the P1 position
KE Rittle, JC Barrow, KJ Cutrona, KL Glass…
Index: Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 20 p. 3477 - 3482
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Citation Number: 27
Abstract
... Bioorganic & Medicinal Chemistry Letters. ... a Department of Medicinal Chemistry, Merck Research ... b Department of Biological Chemistry, Merck Research Laboratories, West Point, PA 19486, USA; c Department of Structural Biology, Merck Research Laboratories, West Point, PA ...
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