Tetrahedron: Asymmetry

Stereoinversion of arylethanols by Geotrichum candidum

K Nakamura, M Fujii, Y Ida

Index: Nakamura, Kaoru; Fujii, Mikio; Ida, Yoshiteru Tetrahedron Asymmetry, 2001 , vol. 12, # 22 p. 3147 - 3153

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Citation Number: 70

Abstract

Homochiral secondary alcohols are increasingly recognized as valuable chiral building blocks in organic syntheses. In the synthesis of enantiomerically pure alcohols, ketones or racemic alcohols are generally used as starting materials. The reduction of prochiral ketones by chemical or enzymatic methods can provide optically active alcohols in quantitative yield with 100% enantiomeric excess (ee). In contrast, the chemical yield of enantiopure alcohols obtained by resolution of ...

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