Carbohydrate research

… acid, 2-methyl-6-(5-acetamido-3, 5-dideoxy-α-d-glycero-d-galacto-nonulopyranosyl-onic acid) xanthene-9-spiro-1′-isobenzofuran-3′-one, a new substrate for …

J Rothermel, H Faillard

Index: Rothermel, Joerg; Faillard, Hans Carbohydrate Research, 1990 , vol. 196, # 1 p. 29 - 40

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Citation Number: 49

Abstract

Abstract Glycosidation of N-acetylneuraminic acid by phase-transfer catalysis in chloroform- aqueous alkali gave several known and some new aryl α-ketosides in a short reaction time and in good yields. The 4-methylumbelliferyl α-ketoside, the standard substrate for neuraminidase, was prepared in a yield of up to 70%. New Neu5Ac ketosides were prepared with fluorescein and the fluorescein analog, 2-methyl-6-hydroxyfluoran (2- ...

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