The Journal of organic chemistry

Synthesis of cis-4-trifluoromethyl-and cis-4-difluoromethyl-L-pyroglutamic acids

XL Qiu, FL Qing

Index: Hon, Yung-Son; Chang, Yen-Chung; Gong, Ming-Li Heterocycles, 1990 , vol. 31, # 2 p. 191 - 195

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Citation Number: 32

Abstract

... Volume: Page ... The combined organic phases were washed with H 2 O and brine and dried over anhydrous Na 2 SO 4 . After removal of the solvent in ... Mp 58−60 °C; [α] 20 D −72.4 (c 0.80, CHCl 3 ); 1 H NMR (300 MHz, CDCl 3 ) δ 4.31−4.19 (m, 1H), 3.95−3.76 (tt ...