Antiviral activity of 1-amino-1, 2, 3, 4-tetrahydrocarbazoles

TV Akalaeva, AI Bokanov, PY Ivanov…

Index: Akalaeva, T. V.; Bokanov, A. I.; Ivanov, P. Yu.; Nikolaeva, I. S.; Pushkina, T. V.; et al. Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 3 p. 231 - 234 Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 3 p. 299 - 302

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Abstract

The syntheses were carried out according to a general scheme: reaction of ketocarbazoles (XXII) with primary amines yielded l-iminotetrahydrocarbazoles (XIIi-XXi),* which were reduced to amino compounds XII-XX. Some of the iminotetrahydrocarbazoles were isolated in the form of their hydrochlorides (Table i). Reductions of the hydrochlorides and the free basis proceed under the same conditions: in ethanol at room temperature with an ...