Chinese Chemical Letters

Synthesis of new hyodeoxycholic acid thiosemicarbazone derivatives under solvent-free conditions using microwave

ZC Shi, ZG Zhao, XL Liu, Y Chen

Index: Shi, Zhi Chuan; Zhao, Zhi Gang; Liu, Xing Li; Chen, Yu Chinese Chemical Letters, 2011 , vol. 22, # 4 p. 405 - 408

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Citation Number: 15

Abstract

An efficient and simple method for synthesis of new hyodeoxycholic acid thiosemicarbazone derivatives under solvent-free conditions using microwave has been developed. Its main advantages are short reaction times, good conversions and the environmentally friendly nature of the process. The preliminary results indicate that some of these compounds possess inhibitory effects against E. coli.

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