Organic letters

Hydrocarbon oxidation vs CC bond-forming approaches for efficient syntheses of oxygenated molecules

KJ Fraunhoffer, DA Bachovchin, MC White

Index: Fraunhoffer, Kenneth J.; Bachovchin, Daniel A.; White, M. Christina Organic Letters, 2005 , vol. 7, # 2 p. 223 - 226

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Citation Number: 90

Abstract

A hydrocarbon oxidation approach has been applied to the construction of several linear (E)- allylic alcohols that have served as intermediates in the synthesis of natural products and natural product-like molecules. In the original syntheses, these intermediates were constructed using a standard Wittig-type olefination approach. We report here that routes to these same intermediates designed around a hydrocarbon oxidation approach are more ...