Synthesis and neuroprotective activity of analogues of glycyl-l-prolyl-l-glutamic acid (GPE) modified at the α-carboxylic acid

NS Trotter, MA Brimble, PWR Harris, DJ Callis…

Index: Bioorganic and Medicinal Chemistry, , vol. 13, # 2 p. 501 - 517

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Citation Number: 30

Abstract

... Bioorganic & Medicinal Chemistry. ... Neuren Pharmaceuticals Medicinal Chemistry Group, Department ... Based on these scientific findings, it has been proposed that GPE 1, or analogues thereof, may provide a novel class of pharmaceutical agents for the treatment of CNS injuries ...