Sequential Suzuki/Asymmetric Aldol and Suzuki/Knoevenagel Reactions Under Aqueous Conditions
M Gruttadauria, LA Bivona, P Lo Meo…
Index: Gruttadauria, Michelangelo; Bivona, Lucia Anna; Lo Meo, Paolo; Riela, Serena; Noto, Renato European Journal of Organic Chemistry, 2012 , # 13 p. 2635 - 2642
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Citation Number: 7
Abstract
Abstract Here we describe for the first time a sequential Suzuki/asymmetric aldol reaction. Such sequential approach was achieved through the combined use of an ionic liquid supported palladium catalyst and the organocatalyst trans-4-(2, 2-diphenylacetoxy) proline. Suzuki and asymmetric aldol reactions were performed under aqueous conditions. The use of a palladium catalyst under basic conditions allowed also the first example of sequential ...
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