5-Nitro-heteroarylidene analogs of 2-thiazolylimino-4-thiazolidinones as a novel series of antibacterial agents

…, N Abadian, Y Mahmoudjanlou, A Sakhteman…

Index: Hosseinzadeh, Nouraddin; Hasani, Mohammad; Foroumadi, Alireza; Nadri, Hamid; Emami, Saeed; Samadi, Nasrin; Faramarzi, Mohammad Ali; Saniee, Parastoo; Siavoshi, Farideh; Abadian, Neda; Mahmoudjanlou, Yasaman; Sakhteman, Amirhossein; Moradi, Alireza; Shafiee, Abbas Medicinal Chemistry Research, 2013 , vol. 22, # 5 p. 2293 - 2302

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Citation Number: 7

Abstract

Abstract In the pursuit of novel antibacterial agents with the 2-thiazolylimino-4-thiazolidinone as a core structure, a series of 5-nitro-heteroarylidene and 5-(2-oxoindolin-3-ylidene) analogs of 2-thiazolylimino-5-arylidene-4-thiazolidinone were synthesized and their antibacterial activities were evaluated against some strains of Gram-positive and Gram- negative bacteria, as well as Helicobacter pylori strains. Biological data indicated that 5- ...

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