Metabolism of theophylline and its inhibition by fluoroquinolones in rat hepatic microsomes

JD Davis, L Aarons, JB Houston

Index: Xenobiotica, , vol. 25, # 6 p. 563 - 573

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Citation Number: 10

Abstract

XENOBIOTICA, 1995, VOL. ... To achieve the appropriate inhibitor concentration in the reaction vessel the required volume of 20 mM ENOX was mixed with an equivalent volume of 1.0 M HCI and diluted to lOml with phosphate buffer, pH7-4. Of this solution, 2pl was taken, to ...