A facile approach to substituted acrylates by regioselective and stereoselective addition of thiols and amines to an alkynyl ester in water
NA Randive, V Kumar, VA Nair
Index: Randive, Nitin A.; Kumar, Varun; Nair, Vipin A. Monatshefte fur Chemie, 2010 , vol. 141, # 12 p. 1329 - 1332
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Citation Number: 8
Abstract
Abstract Water-promoted hydrothiolation and hydroamination of ethyl propiolate leading to highly regioselective and stereoselective formation of thioacrylates and β-enamino esters in excellent yields, by a simple, efficient, and environmentally friendly reaction procedure without employing any hazardous reagent or solvent is reported. Graphical Abstract
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