Phenylpyrroles, a new chemolibrary virtual screening class of 5-HT 7 receptor ligands

…, F Fabis, A Lepailleur, R Bureau, S Butt-Gueulle…

Index: Paillet-Loilier, Magalie; Fabis, Frederic; Lepailleur, Alban; Bureau, Ronan; Butt-Gueulle, Sabrina; Dauphin, Francois; Delarue, Catherine; Vaudry, Hubert; Rault, Sylvain Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 16 p. 3753 - 3757

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Citation Number: 33

Abstract

Virtual screening studies have identified a series of phenylpyrroles as novel 5-HT 7 receptor ligands. The synthesis and the affinity for the 5-HT 7 receptor of these phenylpyrroles are described. Some of these compounds exhibited high affinity for the 5-HT 7 receptors. ... Virtual screening studies have identified a series of phenylpyrroles as novel 5-HT 7 receptor ligands. The synthesis and the affinity for the 5-HT 7 receptor of these phenylpyrroles are ...