Journal of heterocyclic chemistry

Synthesis of [1] benzothieno [3, 2??d] pyrimidines substituted with electron donating substituents on the benzene ring

AJ Bridges, H Zhou

Index: Journal of Heterocyclic Chemistry, , vol. 34, # 4 p. 1163 - 1172

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Citation Number: 21

Abstract

... Heterocyclic Chem., 34, 1163 (1997 ... MeO d, R = 7-MeO e, R = 8-MeO g, R = 8-N02 h, R = 7-NHEt-8-F i, R = 7-NH2-8-F j, R = 7 ... the 7-amino-8-fluoro substitution pattern, starting with 2,4,5-trifluorobenzonitrile 16 as it was felt that the extra fluorine would improve the chemistry ...

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