Tetrahedron

The synthesis and assay of radiolabelled benzene derivatives

NJ Hales, H Heaney, JH Hollinshead, SV Ley

Index: Hales, Neil J.; Heaney, Harry; Hollinshead, John H.; Ley, Steven V. Tetrahedron, 1995 , vol. 51, # 28 p. 7741 - 7754

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Citation Number: 13

Abstract

Several new syntheses of 1and 4-[14C] anisole have been investigated and routes from [14C] cyanide and from 2-[14C] acetone are described which are better than those previously reported. The key step in one of the syntheses was catalytic dehydrogenation of 1- [14C] cyclohexanone to 1-[14C] phenol. Degradation of 5, 6, 7, 8-tetrachloro-3, 4-dihydro-1, 4-etheno-[14C] naphthalen-2 (1H)-one (10) prepared from [14C] anisole and ...

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