Hydrogen peroxide oxidation of aldehydes to carboxylic acids: an organic solvent-, halide-and metal-free procedure

K Sato, M Hyodo, J Takagi, M Aoki, R Noyori

Index: Sato, Kazuhiko; Hyodo, Mamoru; Takagi, Junko; Aoki, Masao; Noyori, Ryoji Tetrahedron Letters, 2000 , vol. 41, # 9 p. 1439 - 1442

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Citation Number: 117

Abstract

Ignoring the ability of aqueous H 2 O 2 to oxidize aldehydes, tremendous efforts have been made to develop metal-based catalysts 4 and inorganic 5 or organic promoters 6 for the oxidation of aldehydes. In 1941, Späth found that H 2 O 2 reacts with dodecanal to form a perhydrate, which decomposes slowly at 120°C to give dodecanoic acid. 7 Since then aqueous H 2 O 2 has been considered to have a weak ability to oxidize aldehydes. Some benzaldehyde derivatives ...