Kinetic studies and modeling of a self-replicating system

JS Nowick, Q Feng, T Tjivikua, P Ballester…

Index: Nowick, James S.; Feng, Qing; Tjivikua, Tjama; Ballester, Pablo; Rebek Jr., Julius Journal of the American Chemical Society, 1991 , vol. 113, # 23 p. 8831 - 8839

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Citation Number: 133

Abstract

Abstract: The design, synthesis, and study of a molecular template, 1 la, that catalyzes its own formation from simpler components, 9 and lOd, is described. Autocatalysis is shown by the following:(1) the increase in rate of reaction of 9 and 1Od in the presence of Ila;(2) the reduction in rate of reaction in the presence of 2, 6-bis (acetylamino) pyridine inhibitor; and (3) the reduction in rate of reaction when a component incapable of template behavior, ...