Evaluation of some classical hydrazones of ketones and 1, 2-diketones as antileishmanial, antibacterial and antifungal agents

YMSA Al-kahraman, M Yasinzai, GS Singh

Index: Al-Kahraman, Yasser M.S.A.; Yasinzai, Masoom; Singh, Girija S. Archives of Pharmacal Research, 2012 , vol. 35, # 6 p. 1009 - 1013

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Citation Number: 8

Abstract

Abstract The paper describes the synthesis and antimicrobial (antileishmanial, antibacterial and antifungal) activity of some classical hydrazones of benzophenones and of 1, 2- diketones. N-(Diaryl) acyl derivatives of these hydrazones have also been synthesized and evaluated. 4, 4,-Demthoxybenzil monohydrazone and 4, 4′-dimethoxybenzophenone hydrazone showed significant antileishmanial activity. The effect of substituents on the ...