New Cycloadditions of (E)??N, α??Dimethyl?螃窿?(4??[2.2] paracylophanyl) nitrone

AA Aly, H Hopf, L Ernst, I Dix…

Index: Aly, Ashraf A.; Hopf, Henning; Ernst, Ludger European Journal of Organic Chemistry, 2000 , # 17 p. 3021 - 3029

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Citation Number: 11

Abstract

Abstract When N, α-dimethyl-α-(4-[2.2] paracyclophanyl) nitrone (1) is treated with dimethyl acetylenedicarboxylate (5), phenyl isocyanate (9), benzyne (13), or ethyl propiolate (16), the [2.2] paracyclophane-based pyrrole 6, imidazole 10, and isoxazole derivatives 14, 15, and 17 are formed in good yields. The stereoisomeric benzisoxazoles 14 and 15 obtained from the reaction between 1 and benzyne (13) could be separated and the structure of one of ...