Highly Selective Claisen–Schmidt Condensation Catalyzed by Silica Chloride Under Solvent-Free Reaction Conditions

…, P Kumar, KS Kondiram, IM Shafi Gadwal

Index: Hazarkhani, Hassan; Kumar, Pradeep; Kondiram, Kadam Sachin; Shafi Gadwal, Ikhlas M. Synthetic Communications, 2010 , vol. 40, # 19 p. 2887 - 2896

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Citation Number: 18

Abstract

The Claisen–Schmidt condensation is an important reaction for the preparation of α,α′-bisarylidene and alkylidene cycloalkanones and chalcones. Arylidende and alkylidene cycloalkanones are important precursors for potentially bioactive pyrimidine derivatives; [ 1 1. Deli , J. ; Lorand , T. ; Szabo , D. ; Foldesi , A. Potential bioactive pyrimidine derivatives, part 1: 2-Amino-4-aryl-8 -arylidene-3,4,5,6,7,8-hexahydroquinazolines . Pharmazie 1984 , 39 , 539 . [PubMed], ...