The Journal of Organic Chemistry

Low valent titanium mediated imino-pinacol coupling: an improved and expeditious route to vicinal diamino-based ligands

S Talukdar, A Banerji

Index: Talukdar, Sanjay; Banerji, Asoke Journal of Organic Chemistry, 1998 , vol. 63, # 10 p. 3468 - 3470

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Citation Number: 54

Abstract

Vicinal diamines find extensive applications in radiopharmaceuticals1a-c and as complexing agents and chiral auxiliaries. 2a, b In connection with our ongoing program on nuclear medicine, an efficient route to vicinal diaminobased ligands was needed. Recently, we have been exploring the potential of low valent titanium (LVT) induced carbonyl-olefin McMurry coupling reaction in a multitude of synthetic endeavors. 3, 4a-f Although ...

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