Synthesis of the N??Substituted Pyridin??1 (2H)??one Framework by Ligand??Assisted Pd??Catalyzed Reactions

…, P Wen, W Chen, C Ma, G Huang

Index: Zhou, Kang; Wen, Ping; Chen, Wenlin; Ma, Chaowei; Huang, Guosheng European Journal of Organic Chemistry, 2013 , # 3 p. 448 - 452

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Abstract

Abstract An efficient Pd-catalyzed method for the synthesis of N-substituted pyridin-1 (2H)- ones was developed. The corresponding derivatives, which can be found in numerous biologically active compounds, were obtained in good to excellent yields. A possible mechanism for this reaction is discussed.