Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter. Part 1

…, S Chu, BC Lee, DY Chi, YS Choe, KJ Jeong…

Index: Lee, Byoung Se; Chu, Soyoung; Lee, Byung Chul; Chi, Dae Yoon; Choe, Yearn Seong; Jeong, Kyung Ja; Jin, Changbae Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 14 p. 1559 - 1562

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Citation Number: 25

Abstract

6-Nitroquipazine has been known as one of the most potent and selective inhibitors of serotonin transporter in vitro and in vivo. Nine derivatives of 6-nitroquipazine were synthesized and tested for their potential abilities to displace [3H] citalopram binding to the rat cortical membranes.