Study of the chemoselectivity of Grignard reagent addition to substrates containing both nitrile and Weinreb amide functionalities

K Harikrishna, A Rakshit…

Index: European Journal of Organic Chemistry, , # 22 p. 4918 - 4932

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Citation Number: 5

Abstract

... Issue. European Journal of Organic Chemistry. ... at the C-2 position in product 17a is evident from the 1 H NMR spectrum; the C-2 proton in the starting substrate 17 resonates at 4.46 ppm (d, J 2,3 = 2.8 Hz, CHCO), whereas that in the product appears at 4.77 ppm (d, J 2,3 = 2.4 ...

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