Tetrahedron letters

Concise total synthesis of (+)-carpamic acid

S Randl, S Blechert

Index: Randl, Stefan; Blechert, Siegfried Tetrahedron Letters, 2004 , vol. 45, # 6 p. 1167 - 1169

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Citation Number: 35

Abstract

We report herein an efficient enantioselective synthesis of (+)-carpamic acid, with nine steps as the longest linear sequence, the key strategy being based on a novel sequence of a cross-metathesis (CM) reaction and a subsequent cyclizing reductive amination to form the piperidine ring.

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