Synthesis of Pyridine and Isoquinoline Derivatives by the Palladium-Catalyzed Cyclization of Olefinic Ketone O-Pentafluorobenzoyloximes.

H Tsutsui, K Narasaka

Index: Tsutsui, Hironori; Narasaka, Koichi Chemistry Letters, 2001 , # 6 p. 526 - 527

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Citation Number: 37

Abstract

Recently, we have reported the oxidative addition of oxime derivatives to palladium(0) complex to generate alkylidene- aminopalladium(II) species.1,2 This process was applied to the transformation of γ,δ-unsaturated ketone O-pentafluorobenzoyl- oximes to pyrroles by the Heck-type cyclization, and the reac- tion proceeded regardless of the E/Z stereochemistry of O- pentafluorobenzoyloximes. In order to prepare functionalized pyrroles, 3-methoxy-1- ...