Synthesis of Novel Coumarin-Based Fluorescent Probes

I Kosiova, P Kois

Index: Kosiova, Ivana; Kois, Pavol Collection of Czechoslovak Chemical Communications, 2007 , vol. 72, # 8 p. 996 - 1004

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Citation Number: 5

Abstract

Abstract We report on synthesis of new fluorescent probes suitable for site-specific incorporation into oligonucleotides. Coumarin derivatives were used as sensitive fluorescent labels and were attached to glycerol unit by two types of linkers as potential building blocks for oligonucleotide synthesis. Spectral characteristics of the functionalized coumarin building blocks were measured.