Synthesis of N??Arylamides by Copper??Catalyzed Amination of Aryl Halides with Nitriles
…, LG Liao, C Feng, BQ Wang, KQ Zhao…
Index: Xiang, Shi-Kai; Zhang, Dong-Xue; Hu, Hao; Shi, Jiang-Ling; Liao, Li-Guo; Feng, Chun; Wang, Bi-Qin; Zhao, Ke-Qing; Hu, Ping; Yang, Hua; Yu, Wen-Hao Advanced Synthesis and Catalysis, 2013 , vol. 355, # 8 p. 1495 - 1499
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Citation Number: 15
Abstract
Abstract A copper-catalyzed amination of aryl halides with nitriles has been developed. The use of nitriles as nitrogen nucleophiles can make the synthesis of N-arylamides more simple than that using amides through in-situ hydrolysis. A variety of N-arylamides and benzoxazole derivatives can be synthesized according to this approach.
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