Diversity-oriented synthesis of biaryl-containing medium rings using a one bead/one stock solution platform

…, S Krishnan, HE Blackwell, SL Schreiber

Index: Spring, David R.; Krishnan, Shyam; Blackwell, Helen E.; Schreiber, Stuart L. Journal of the American Chemical Society, 2002 , vol. 124, # 7 p. 1354 - 1363

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Citation Number: 163

Abstract

Diversity-oriented synthesis of structurally complex and diverse small molecules can be used as the first step in a process to explore cellular and organismal pathways. The success of this process is likely going to be dependent on advances in the synthesis of small molecules having natural product-like structures in an efficient and stereoselective manner. The development, scope, and mechanism of the oxidation of organocuprates was ...