Molecular design, synthesis and neuroleptic activity of dipeptide analogs of sulpride

…, NI Zaitseva, NA Bondarenko, IÉ Scherbakova…

Index: Gudasheva; Zaitseva; Bondarenko; Shcherbakova; Asmakova; Rozantsev; Ostrovskaya; Voronina; Seredenin Pharmaceutical Chemistry Journal, 1998 , vol. 32, # 11 p. 574 - 580

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Citation Number: 2

Abstract

Some nonpeptide psychotropic drugs are known to repre- sent the ligands of the corresponding neuropeptide receptors. For example, morphine acts via the enkephalin receptors [1], while the benzodiazepine tranquilizers are the ligands of the DBI peptide receptors [2]. This circumstance gives us a pos- sibility to synthesize biologically active short-chain peptides that are structural analogs of the known neurotropic agents and may serve as base structures for the ...