Convenient syntheses of fluorenylmethyl-based side chain derivatives of glutamic and aspartic acids, lysine, and cysteine

…, E Nicolas, J Rizo, M Ruiz-Gayo, E Pedroso, E Giralt

Index: Albericio, F.; Nicolas, E.; Rizo, J.; Ruiz-Gayo, M.; Pedroso, E.; Giralt, E. Synthesis, 1990 , # 2 p. 119 - 122

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Citation Number: 48

Abstract

Efficient and practical one-pot syntheses of the fluorenylmethylbased side chain derivatives of glutamic and aspartic acids, lysine, and cysteine are described. Likewise, stability/lability of these derivatives towards solvents and reagents used in solid phase peptide synthesis are discussed. In this paper, we describe an efficient and practical one—pot syntheses of the fluorenylmethyl (Fm) based side chain derivatives of glutamic and aspartic acids, lysine, ...