AN IMPROVED SYNTHESIS OF N∊-FMOC-L-LYSINE AND Nδ-FMOC-L-ORNITHINE

M Henczi, DF Weaver

Index: Henczi, Maria; Weaver, Donald F. Organic Preparations and Procedures International, 1994 , vol. 26, # 5 p. 578 - 580

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Citation Number: 8

Abstract

The selective introduction of a readily removed mine protecting group into the side-chnin of a dibasic amino acid petinits the synthetically desirable objective of sidechain modification to a" nonnntural/atypical" residue following the synthesis of the backbone. The 9- fluorenylmethoxycarhonyl (Ftnoc) group, which is easily deblocked under mild basic conditions' and is compatihle with either t-