Studies on an (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl) propionic acid (AMPA) receptor antagonist IKM-159: asymmetric synthesis, neuroactivity, and structural …

L Juknaitė, Y Sugamata, K Tokiwa, Y Ishikawa…

Index: Cluzeau, Jerome; Oishi, Shinya; Ohno, Hiroaki; Wang, Zixuan; Evans, Barry; Peiper, Stephen C.; Fujii, Nobutaka Organic and Biomolecular Chemistry, 2007 , vol. 5, # 12 p. 1915 - 1923

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Citation Number: 14

Abstract

... Yokohama 236-0027, Japan. ‡ Department of Molecular Pharmacology and Biological Chemistry, Northwestern University ... Chemical Synthesis The asymmetric synthesis was carried out on the basis of our ... wherein the 4-methoxybenzyl group had been removed at −10 °C in 71 ...