Chemistry–A European Journal

Intramolecular hydroarylation of alkynes catalyzed by platinum or gold: Mechanism and endo selectivity

C Nevado, AM Echavarren

Index: Nevado, Cristina; Echavarren, Antonio M. Chemistry - A European Journal, 2005 , vol. 11, # 10 p. 3155 - 3164

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Citation Number: 238

Abstract

Abstract The cyclization of differently substituted aryl alkynes with Pt II or Au I catalysts proceeds by endo-dig pathways. When Ag I was used to generate reactive cationic Au I catalysts, 2H-chromenes dimerize to form cyclobutane derivatives by a Ag I-catalyzed process. A DFT study on the cyclization mechanism shows a kinetic and thermodynamic preference for 6-endo-dig versus 5-exo-dig cyclizations in Pt II-catalyzed processes. ...

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