Total synthesis of indole and dihydroindole alkaloids. V. Total synthesis of dl-quebrachamine and dl-aspidospermidine. General entry into the aspidosperma alkaloids

JP Kutney, N Abdurahman, C Gletsos…

Index: Kutney,J.P. et al. Journal of the American Chemical Society, 1970 , vol. 92, # 6 p. 1727 - 1735

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Citation Number: 58

Abstract

Abstract: The total synthesis of dl-quebrachamine and dl-aspidospermidine is described. The synthetic sequence parallels the pathway employed for the total synthesis of the dihydrocleavamine skeleton in which the nine-membered ring system is generated in the final step via a reductive cleavage reaction. he previous publication in this series2 has described T in detail a total synthesis of the dl-dihydrocleavamines and the carbomethoxy ...