Grignard Reactions. XVII. 1 The Reactions of Esters and Acid Chlorides with Grignard Reagents
FC Whitmore, WS Forster
Index: Whitmore; Forster Journal of the American Chemical Society, 1942 , vol. 64, p. 2967
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Citation Number: 11
Abstract
In the course of the preparation of large amounts of diethyl-t-butylcarbinol, it was found that while ethylmagnesium bromide reacted with trimethylacetyl chloride to give 26% of this tertiary alcohol and GO% of the secondary alcohol, ethyl-t-butylcarbinol, the same reagent reacted with methyl trimethylacetate to give 78.5% of the tertiary alcohol and only 8.6% of the secondary alcohol.
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