A convenient synthesis of optically active 1H-aziridine-2-carboxylic acids (esters)
J Legters, L Thijs, B Zwanenburg
Index: Legters, J.; Thijs, L.; Zwanenburg, B. Tetrahedron Letters, 1989 , vol. 30, # 36 p. 4881 - 4884
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Citation Number: 112
Abstract
Abstract Optically active glycidic esters, prepared from allylic alcohols employing the Sharpless epoxidation, were treated with sodium azide. In a subsequent reaction with PPh 3 the azido alcohols thus obtained were converted into aziridine-2-carboxylic esters of high optical purity in good yields.
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